These are the headlines you Need2Know:

  • Joining Forces to Fight Cartels: The United States and Mexico will cooperate to fight drug cartels amid tension between the two countries over President Trump’s immigration policies. The anti-drug plan calls for more aggressively attacking the cartels’ financial infrastructure. For more on this story, click here.

  • Dozens Overdose at Park Near Yale: At least 70 people overdosed Wednesday on a synthetic cannabinoid substance called K2, which was laced with fentanyl. There has not been a reported fatality in the New Haven, Conn., park, but two people are in life-threatening condition. One person has been arrested in connection with selling the drugs. For more, click here.

  • Cake Shop Owner May Go Back to the Supreme Court: The owner of Masterpiece Cakeshop, Jack Phillips, is suing the state of Colorado because he didn't want to make a cake for a transgender woman. Earlier this year, Phillips won a 7-2 Supreme Court decision over his refusal to bake a cake for a same-sex couple because it went against his religious beliefs. Gov. John Hickenlooper, who is named in Phillips' suit, said the new case could also make it to the Supreme Court. For more on this story, check out NPR.

  • Jury to Decide Paul Manafort's Future: Deliberations are underway in the trial of President Trump's former campaign chairman. Manafort pleaded not guilty to all 18 counts of tax evasion, financial fraud, and concealing of foreign accounts. The verdict could possibly determine the course of the investigation by the special counsel Robert Mueller into Russian interference with the 2016 presidential campaign. For more on this story, click here.

Cheddar's Jill Wagner gets into the latest.

Subscribe to the Need2Know newsletter here.